The Registry of Toxic Effects of Chemical Substances

Barium sulfate

RTECS #: CR0600000

CAS #: 7727-43-7

UPDATE: November 2004 MW: 233.40 MF: O4S•Ba


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. TUMORIGENIC DATA:
  4. ACUTE TOXICITY DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. Actybaryte
  2. Artificial barite
  3. Artificial heavy spar
  4. Bakontal
  5. Baridol
  6. Barite
  7. Baritop
  8. A 15 (inorganic compound)
  9. BA147
  10. Blanc fixe
  11. C.I. 77120
  12. C.I. Pigment White 21
  13. Citobaryum
  14. Colonatrast
  15. Enamel White
  16. Esophotrast
  17. Eweiss
  18. E - Z - Paque
  19. Finemeal
  20. Lactobaryt
  21. Liquibarine
  1. Macropaque
  2. Neobar
  3. Oratrast
  4. Permanent White
  5. Precipitated barium sulphate
  6. Raybar
  7. Redi - Flow
  8. Solbar
  9. Sulfuric acid, barium salt (1:1)
  10. Supramike
  11. Travad
  12. Barium sulfate (ACGIH:OSHA)
  13. Barium sulfate (1:1)
  14. Barium sulphate
  15. Barosperse
  16. Barotrast
  17. Baryta White
  18. Barytes
  19. Barytes 22
  20. Bayrites
  21. Unibaryt


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
micronucleus test intraperitoneal
mouse 		12,500 µg/kg GWZHEW 12,77,1986


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intrapleural
rat 		lowest published toxic dose: 200 mg/kg Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors 		BJCAAI 28,173,1973


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intratracheal
mouse 		lethal dose : >600 µL/kg Lung, Thorax, or Respiration: Other changes OYYAA2 50,123,1995


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 10 mg/m3 DTLVS* TLV/BEI,2003
TOXICOLOGY REVIEW
31BYAP -,94,1974


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg(Ba)/m3 DTLVS* 3,21,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1915.1000,1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 10 mg/m3, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 10 mg/m3 (resp. dust), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - SWEDEN time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg(Ba)/m3, 2003
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 1.5 mg/m3 (respirable dust), 2003
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 4 mg/m3 (total dust), 2003
Occupational Exposure Limit - UNITED KINGDOM time-weighted average (Respirable dust) 4 mg(Ba)/m3, SEP2000
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 10 mg(Ba)/m3 (total dust), SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 10 mg/m3
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 10 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO BARIUM SULFATE, respirable fraction-air 10 hour time-weighted average 5 mg/m3 NIOSH* DHHS #92-100,1992
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO BARIUM SULFATE, total dust-air 10 hour time-weighted average 10 mg/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80611;
Number of Industries 173;
Total Number of Facilities 18,620;
Number of Occupations 104;
Total Number of Employees Exposed 188,781
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80611;
Number of Industries 200;
Total Number of Facilities 25,446;
Number of Occupations 133;
Total Number of Employees Exposed 363,169;
Total Number of Female Employees Exposed 96,327


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as raw material source of BARIUM
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
31BYAP "Experimental Lung Cancer: Carcinogenesis and Bioassays, International Symposium, 1974," Karbe, E., and J.F. Park, eds., Springer-Verlag New York, Inc., 1974
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
GWZHEW Gongye Weisheng Yu Zhiyebing. Industrial Health and Occupational Diseases. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1973-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967-

Used as raw material source of BARIUM

NIOSH PROFILE (BARIUM and ITS COMPOUNDS), SRI, 2/77

RTECS Compound Description:
   Tumorigen
   Drug
   Mutagen

ALT CAS #: 8054-35-1
ALT CAS #: 12751-32-5
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