The Registry of Toxic Effects of Chemical Substances
Barium (II) nitrate (1:2) |
UPDATE: November 2004 | MW: 261.36 | MF: N2O6•Ba |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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eye | rabbit
100 mg/24 hour
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moderate
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28ZPAK -,10,1972
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skin | rabbit
500 mg/24 hour
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mild
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28ZPAK -,10,1972
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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intraperitoneal | mouse
lethal dose (50 percent kill): 293 mg/kg
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Autonomic Nervous System: Other (direct) parasympathomimetic | Behavioral: Muscle weakness Gastrointestinal: Nausea or vomiting
GTPZAB 28(6),45,1984
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intraperitoneal | rat
lethal dose (50 percent kill): 293 mg/kg
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Behavioral: Somnolence (general depressed activity) | Behavioral: Tetany
VCVN1* -,136,1988
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intravenous | mouse
lethal dose (50 percent kill): 16 mg/kg
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N/R
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TXAPA9 22,150,1972
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oral | dog
lowest published lethal dose: 800 mg/kg
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N/R
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YKYUA6 31,1247,1980
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oral | mammal (species unspecified)
lethal dose (50 percent kill): 390 mg/kg
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Autonomic Nervous System: Other (direct) parasympathomimetic | Behavioral: Muscle weakness Gastrointestinal: Nausea or vomiting
GTPZAB 28(6),45,1984
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oral | man
lowest published toxic dose: 83 mg/kg
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Peripheral Nerve and Sensation: Paresthesia | Behavioral: Muscle weakness Nutritional and Gross Metabolic: Changes in: K
JTCTDW 38,254,2000
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oral | mouse
lethal dose (50 percent kill): 266 mg/kg
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N/R
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EVHPAZ 106(Suppl 2),497,1998
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oral | rat
lethal dose (50 percent kill): 355 mg/kg
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N/R
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28ZPAK -,10,1972
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oral | rat
lethal dose (50 percent kill): 390 mg/kg
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Behavioral: Somnolence (general depressed activity) | Behavioral: Tetany
VCVN1* -,136,1988
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oral | rabbit
lowest published lethal dose: 150 mg/kg
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N/R
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YKYUA6 31,1247,1980
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parenteral | rabbit
lowest published lethal dose: 30 mg/kg
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Gastrointestinal: Hypermotility, diarrhea | Kidney, Ureter, and Bladder: Urine volume increased
MELAAD 30,44,1939
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subcutaneous | mouse
lowest published lethal dose: 10 mg/kg
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N/R
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NTIS** AEC-TR-6710
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
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N/R
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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time-weighted average 0.5 mg(Ba)/m3
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DTLVS* TLV/BEI,1999
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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Not classifiable as a human carcinogen
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DTLVS* TLV/BEI,1999
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air
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time-weighted average 0.5 mg(Ba)/m3
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DTLVS* 3,21,1971
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)
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8 hour time-weighted average 0.5 mg(Ba)/m3
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CFRGBR 29,1910.1000,1994
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)
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8 hour time-weighted average 0.5 mg(Ba)/m3
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CFRGBR 29,1926.55,1994
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)
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8 hour time-weighted average 0.5 mg(Ba)/m3
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CFRGBR 29,1915.1000,1993
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Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)
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8 hour time-weighted average 0.5 mg(Ba)/m3
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CFRGBR 41,50-204.50,1994
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Occupational Exposure Limit - AUSTRALIA
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time-weighted average 0.5 mg(Ba)/m3, JAN1993
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Occupational Exposure Limit - AUSTRIA
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MAK 0.5 mg(Ba)/m3, JAN1999
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Occupational Exposure Limit - BELGIUM
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time-weighted average 0.5 mg(Ba)/m3, JAN1993
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Occupational Exposure Limit - DENMARK
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time-weighted average 0.5 mg(Ba)/m3, JAN1999
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Occupational Exposure Limit - FINLAND
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time-weighted average 0.5 mg(Ba)/m3, JAN1999
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Occupational Exposure Limit - FRANCE
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VME 0.5 mg(Ba)/m3, JAN1999
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Occupational Exposure Limit - GERMANY
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MAK 0.5 mg(Ba)/m3, JAN1999
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Occupational Exposure Limit - HUNGARY
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short term exposure limit 0.5 mg(Ba)/m3, JAN1993
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Occupational Exposure Limit - THE NETHERLANDS
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MAC-TGG 0.5 mg(Ba)/m3, 2003
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Occupational Exposure Limit - NORWAY
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time-weighted average 0.5 mg(Ba)/m3, JAN1999
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Occupational Exposure Limit - THE PHILIPPINES
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time-weighted average 0.5 mg(Ba)/m3, JAN1993
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Occupational Exposure Limit - POLAND
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time-weighted average 0.5 mg(Ba)/m3, short term exposure limit 1.5 mg(Ba)/m3, JAN1999
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Occupational Exposure Limit - RUSSIA
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short term exposure limit 0.5 mg/m3, JAN1993
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Occupational Exposure Limit - TURKEY
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time-weighted average 0.5 mg(Ba)/m3, JAN1993
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Occupational Exposure Limit - UNITED KINGDOM
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time-weighted average 0.4 mg(Ba)/m3, SEP2000
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Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value; | Not classifiable as a human carcinogen
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value |
Not classifiable as a human carcinogen |
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: 81720; | Number of Industries 12; Total Number of Facilities 542; Number of Occupations 13; Total Number of Employees Exposed 2,705
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: 81720; |
Number of Industries 23; Total Number of Facilities 600; Number of Occupations 26; Total Number of Employees Exposed 19,320; Total Number of Female Employees Exposed 5,165 |
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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REFERENCES:
CODEN
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REFERENCE
28ZPAK
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"Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro
Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
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CFRGBR
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Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents,
Washington, DC 20402)
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DTLVS*
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The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by
American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
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EVHPAZ
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EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents,
Washington, DC 20402) No.1- 1972-
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GTPZAB
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Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see
MTPEEI
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JTCTDW
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Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY
10016) V.19- 1982-
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MELAAD
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Medicina del Lavoro. Industrial Medicine. (Via S. Barnaba, 8, 20122 Milan, Italy) V.16-
1925-
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NTIS**
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National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information.
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TXAPA9
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Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1959-
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VCVN1*
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"Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous
substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.
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YKYUA6
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Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950-
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