The Registry of Toxic Effects of Chemical Substances

Bacillus subtilis carlsberg

RTECS #: CO9550000

CAS #: 9014-01-1

UPDATE: May 2004 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. ALK - enzyme
  2. Alcalase
  3. Bacillopeptidase A
  4. Bacillopeptidase B
  5. Bioprase
  6. Colistinase
  7. E.C. 3.4.21.14
  8. E.C. 3.4.4.16
  9. Maxatase
  10. Nagarse
  11. SP 266
  1. Subtilisin (9CI)
  2. Subtilisin (ACGIH)
  3. Subtilisin NOVO
  4. Subtilisin bpn'
  5. Subtilisin carlsburg
  6. Subtilisins
  7. Subtilopeptidase A
  8. Subtilopeptidase B
  9. Subtilopeptidase C
  10. Subtilopeptidase bpn'
  11. Thermoase PC - 10


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		3 mg moderate FCTXAV 7,581,1969


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lethal dose (50 percent kill): 3,700 mg/kg N/R FCTXAV 7,581,1969


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value ceiling concentration 0.00006 mg/m3 DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.0003 mg/m3 DTLVS* 3,236,1971
Occupational Exposure Limit - SWEDEN time-weighted average 1 glycine unit/m3, CEILING 3 glycine units/m3, JAN1999
Occupational Exposure Limit - UNITED KINGDOM LTEL 0.00006 mg/m3, short term exposure limit 0.00006 mg/m3, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

ceiling concentration 0.00006 mg/m3
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
ceiling concentration 0.00006 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO SUBTILISINS-air short term exposure limit 0.00006 mg/m3/60 minute NIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X1796;
Number of Industries 3;
Total Number of Facilities 225;
Number of Occupations 5;
Total Number of Employees Exposed 5,548;
Total Number of Female Employees Exposed 1,814


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8800
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.

RTECS Compound Description:
   Primary Irritant

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