The Registry of Toxic Effects of Chemical Substances

Antimony

RTECS #: CC4025000

CAS #: 7440-36-0

UPDATE: November 2004 MW: 121.75 MF: Sb


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. TUMORIGENIC DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Antimony (ACGIH:OSHA)
  2. Antimony Black
  3. Antimony metal, super - pure
  4. Antimony, regulus
  1. Antymon (Polish)
  2. C.I. 77050
  3. Stibium


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 50 mg/m3/7 hour/52 week- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Lung, Thorax, or Respiration: Tumors 		JTEHD6 18,607,1986


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
human 		lowest published toxic concentration: 13.5 mg/m3/4 hour Olfaction: Other olfaction effects

Blood: Hemorrhage 		VCVN5* -,105,1993
inhalation
human 		lowest published toxic concentration: 10 mg/m3/8 hour Behavioral: Muscle weakness

Gastrointestinal: Nausea or vomiting

Nutritional and Gross Metabolic: Body temperature increase 		VCVN5* -,105,1993
intraperitoneal
guinea pig 		lethal dose (50 percent kill): 150 mg/kg N/R EQSSDX 1,1,1975
intraperitoneal
mouse 		lethal dose (50 percent kill): 80 mg/kg N/R VCVN5* -,105,1993
intraperitoneal
rat 		lethal dose (50 percent kill): 100 mg/kg N/R 85GMAT -,22,1982
oral
rat 		lethal dose (50 percent kill): 7 gm/kg N/R EQSSDX 1,1,1975


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.5 mg(Sb)/m3 DTLVS* TLV/BEI,2003
TOXICOLOGY REVIEW
FOREAE 7,313,1942
TOXICOLOGY REVIEW
PTPAD4 1,157,1976


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg/m3 DTLVS* 3,14,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.5 mg(Sb)/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.5 mg(Sb)/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.5 mg(Sb)/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.5 mg(Sb)/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - ARAB Republic of Egypt time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 0.5 mg/m3, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.5 mg/m3, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - FRANCE VME 0.5 mg/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.5 mg/m3 (total dust), JAN1993
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg(Sb)/m3, 2003
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg/m3, 2003
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 0.1 mg/m3, 2B Carcinogen, JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 0.5 mg(Sb)/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.5 mg/m3, MAC(short term exposure limit) 1.5 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 0.2 mg/m3, short term exposure limit 0.5 mg/m3, JAN1993
Occupational Exposure Limit - SWEDEN NGV 0.5 mg/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 0.5 mg/m3, JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - UNITED NATIONS time-weighted average 0.5 mg/m3, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.5 mg(Sb)/m3
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.5 mg(Sb)/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ANTIMONY-air 10 hour time-weighted average 0.5 mg(Sb)/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 07310;
Number of Industries 21;
Total Number of Facilities 2,043;
Number of Occupations 26;
Total Number of Employees Exposed 15,083
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X9115;
Number of Industries 2;
Total Number of Facilities 30;
Number of Occupations 3;
Total Number of Employees Exposed 359
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 07310;
Number of Industries 143;
Total Number of Facilities 21,458;
Number of Occupations 99;
Total Number of Employees Exposed 383,579;
Total Number of Female Employees Exposed 139,736


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
ATSDR TOXICOLOGY PROFILE (NTIS** PB/93/110641/AS)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE FEREAC 47,26992,82
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Elements in blood or tissue, 8005
OSHA ANALYTICAL METHOD #ID-125G
OSHA ANALYTICAL METHOD #ID121


REFERENCES:

CODEN
REFERENCE
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
FOREAE Food Research. (Champaign, IL) V.1-25, 1936-60. For publisher information, see JFDSAZ.
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
PTPAD4 Pharmacology and Therapeutics, Part A: Chemotherapy, Toxicology and Metabolic Inhibitors. (Oxford, UK) V.1-2, 1976-78. For publisher information, see PHTHDT.
VCVN5* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.

NIOSH PROFILE (PRINTING INDUSTRY), SRC, 10/77

NIOSH PROFILE (SMELTERS, SECONDARY NON-FERROUS), SRI, 2/77

RTECS Compound Description:
   Tumorigen
   Human Data

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