The Registry of Toxic Effects of Chemical Substances
Acetic acid, sodium salt |
UPDATE: October 1997 | MW: 82.04 | MF: C2H3O2逼a |
SYNONYMS: | |
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SKIN AND EYE IRRITATION DATA AND REFERENCES: | |||
ROUTE/ ORGANISM | DOSE |
EFFECT | REFERENCE |
eye rabbit | 10 mg | mild | BIOFX* 19-3/1971 |
skin rabbit | 500 mg/24 hour | mild | BIOFX* 19-3/1971 |
MUTATION DATA AND REFERENCES: | |||
SYSTEM TEST |
ROUTE/ ORGANISM/ TISSUE | DOSE | REFERENCE |
N/R | N/R | N/R | N/R |
REPRODUCTIVE EFFECTS DATA AND REFERENCES: | |||
ROUTE/ ORGANISM | DOSE |
EFFECT | REFERENCE |
N/R | N/R | N/R | N/R |
TUMORIGENIC DATA AND REFERENCES: | |||
ROUTE/ ORGANISM | DOSE |
EFFECT | REFERENCE |
N/R | N/R | N/R | N/R |
ACUTE TOXICITY DATA AND REFERENCES: | |||
ROUTE/ ORGANISM | DOSE |
EFFECT | REFERENCE |
inhalation rat | lethal concentration (50 percent kill): >30 gm/m3/1 hour | N/R | BIOFX* 19-3/1971 |
intravenous mouse | lowest published lethal dose: 1,195 mg/kg | N/R | JLCMAK 29,809,1944 |
intravenous rabbit | lowest published lethal dose: 1,300 mg/kg |
Behavioral: Toxic psychosis Behavioral: Fluid intake Kidney, Ureter, and Bladder: Urine volume increased | AEXPBL 21,119,1886 |
oral mouse | lethal dose (50 percent kill): 6,891 mg/kg | N/R | JIHTAB 23,78,1941 |
oral rat | lethal dose (50 percent kill): 3,530 mg/kg | N/R | FAONAU 40,126,1967 |
subcutaneous mouse | lethal dose (50 percent kill): 3,200 mg/kg | N/R | TOXIA6 24,553,1986 |
skin rabbit | lethal dose (50 percent kill): >10 gm/kg | N/R | BIOFX* 19-3/1971 |
OTHER MULTIPLE DOSE DATA AND REFERENCES: | |||
ROUTE/ ORGANISM | DOSE |
EFFECT | REFERENCE |
N/R | N/R | N/R | N/R |
REVIEWS: | ||
ORGANIZATION | STANDARD |
REFERENCE |
N/R | N/R | N/R |
STANDARDS AND REGULATIONS: | ||
ORGANIZATION | STANDARD |
REFERENCE |
N/R | N/R | N/R |
NIOSH DOCUMENTATION AND SURVEILLANCE: | ||
ORGANIZATION | STANDARD or SURVEY |
REFERENCE |
National Occupational Hazard Survey 1974 |
National Occupational Hazard Survey 1974: Hazard Code: 68770; Number of Industries 122; Total Number of Facilities 16,581; Number of Occupations 65; Total Number of Employees Exposed 94,994 | |
National Occupational Exposure Survey 1983 |
National Occupational Exposure Survey 1983: Hazard Code: 68770![]() Number of Industries 192; Total Number of Facilities 32,101; Number of Occupations 151; Total Number of Employees Exposed 563,021; Total Number of Female Employees Exposed 247,479 |
STATUS IN FEDERAL AGENCIES: | |
ORGANIZATION |
REFERENCE |
EPA GENETOX PROGRAM 1988, Negative: In vitro SCE-human lymphocytes; In vitro SCE-human | |
EPA TSCA Section 8(b) CHEMICAL INVENTORY | |
Used as a buffer in many chemical intermediates | |
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001 |
REFERENCES: | |
CODEN |
REFERENCE |
AEXPBL | Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. |
BIOFX* | BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810 Frontage Rd., Northbrook, IL 60062) |
FAONAU | FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. |
JIHTAB | Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. |
JLCMAK | Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- |
TOXIA6 | Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- |