The Registry of Toxic Effects of Chemical Substances

Acetic acid, fluoro -

RTECS #: AH5950000

CAS #: 144-49-0

UPDATE: January 1997 MW: 78.05 MF: C2H3FO2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. STATUS IN FEDERAL AGENCIES:
  4. REFERENCES:

SYNONYMS:

  1. Cymonic acid
  2. Fluoroacetate
  3. 2 - Fluoroacetic acid
  4. Fluoroethanoic acid
  5. Gifblaar poison
  6. Monofluorazijnzuur (Dutch)
  1. Monofluoressigsaure (German)
  2. Monofluoroacetate
  3. Monofluoroacetic acid
  4. Acide - monofluoracetique (French)
  5. Acido monofluoroacetio (Italian)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 6,600 µg/kg N/R JOCEAH 21,883,1956
intravenous
mouse 		lethal dose (50 percent kill): 13 mg/kg N/R CSLNX* NX#03014
intravenous
rabbit 		lethal dose (50 percent kill): 250 µg/kg N/R NATUAS 158,382,1946
oral
guinea pig 		lethal dose (50 percent kill): 468 µg/kg N/R TXAPA9 13,189,1968
oral
mouse 		lethal dose (50 percent kill): 7 mg/kg N/R TXAPA9 13,189,1968
oral
rat 		lethal dose (50 percent kill): 4,680 µg/kg N/R TXAPA9 13,189,1968
subcutaneous
mouse 		lethal dose (50 percent kill): 281 mg/kg N/R JPETAB 95,62,1949
subcutaneous
rat 		lethal dose (50 percent kill): 5 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Dyspnea 		TXAPA9 26,93,1973
unreported route
domestic animal 		lowest published lethal dose: 400 µg/kg Cardiac: Other changes 34ZIAG -,274,1969
unreported route
rabbit 		lowest published lethal dose: 500 µg/kg Cardiac: Other changes 34ZIAG -,274,1969


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
JOCEAH Journal of Organic Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1936-
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

RTECS Compound Description:
   Drug

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