The Registry of Toxic Effects of Chemical Substances

Acetic acid, cyclohexyl ester

RTECS #: AG5075000

CAS #: 622-45-7

UPDATE: January 1997 MW: 142.22 MF: C8H14O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Cyclohexanol, acetate
  2. Cyclohexanolazetat (German)
  1. Cyclohexanyl acetate
  2. Cyclohexylester kyseliny octove (Czech)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		500 mg/24 hour mild 85JCAE -,359,1986
skin
rabbit 		500 mg/24 hour moderate FCTXAV 17,751,1979
skin
rabbit 		100 mg/24 hour moderate 85JCAE -,359,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
human 		lowest published toxic concentration: 3,000 mg/m3/45 minute Eye: Conjunctiva irritation

Lung, Thorax, or Respiration: Other changes 		AHYGAJ 78,260,1913
oral
rat 		lethal dose (50 percent kill): 6,730 µL/kg N/R TXAPA9 28,313,1974
subcutaneous
cat 		lowest published lethal dose: 800 mg/kg N/R AHYGAJ 78,260,1913
skin
rabbit 		lethal dose (50 percent kill): 10 mL/kg N/R TXAPA9 28,313,1974


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
TOXICOLOGY REVIEW
AMIHAB 21,28,1960


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AHYGAJ Archiv fuer Hygiene. (Munich, Fed. Rep. Ger.) V.1-100, 1883-1928. For publisher information, see ZHPMAT.
AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU.
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

RTECS Compound Description:
   Human Data
   Primary Irritant

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