International Chemical Safety Cards

RIBOFLAVIN

ICSC: 1454

Lactoflavine
Vitamin B2
C₁₇H₂₀N₄O₆
Molecular mass: 376.4
ICSC # 1454
CAS # 83-88-5
RTECS # VJ1400000
October 10, 2002 Peer reviewed

TYPES OF HAZARD/ EXPOSURE	ACUTE HAZARDS/ SYMPTOMS	PREVENTION	FIRST AID/ FIRE FIGHTING
FIRE	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Coarse water spray, carbon dioxide.
EXPLOSION	Finely dispersed particles form explosive mixtures in air.	Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting.

EXPOSURE		PREVENT DISPERSION OF DUST!
•INHALATION	Cough. Sore throat.	Local exhaust or breathing protection.	Fresh air, rest.
•SKIN		Protective gloves.	Rinse and then wash skin with water and soap.
•EYES	Redness. Pain.	Safety spectacles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION		Do not eat, drink, or smoke during work.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Sweep spilled substance into covered containers; if appropriate, moisten first to prevent dusting.

Well closed.

R:
S:

SEE IMPORTANT INFORMATION ON BACK

ICSC: 1454

Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

RIBOFLAVIN

ICSC: 1454

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PHYSICAL STATE; APPEARANCE:
ORANGE-YELLOW CRYSTALS

PHYSICAL DANGERS:
Dust explosion possible if in powder or granular form, mixed with air.

CHEMICAL DANGERS:
The substance decomposes on heating producing toxic fumes .

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by ingestion.

INHALATION RISK:
A nuisance-causing concentration of airborne particles can be reached quickly when dispersed.

EFFECTS OF SHORT-TERM EXPOSURE:

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

PHYSICAL
PROPERTIES

Melting point (decomposes): 280°C
Solubility in water, g/100 ml at 25°C: 0.01

Octanol/water partition coefficient as log Pow: -1.46

ENVIRONMENTAL
DATA

N O T E S

NFPA Code: H0; F3; R0;

ADDITIONAL INFORMATION

ICSC: 1454	RIBOFLAVIN
(C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE:

Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.