International Chemical Safety Cards NITRIC OXIDE ICSC: 1311 Nitrogen oxide Mononitrogen monoxide NO Molecular mass: 30.01 (cylinder) ICSC #    1311 CAS #     10102-43-9 RTECS # QX0525000 UN #        1660 November 25, 1998 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible but enhances combustion of other substances. In case of fire in the surroundings: use appropriate extinguishing media. EXPLOSION In case of fire: keep cylinder cool by spraying with water. Combat fire from a sheltered position. EXPOSURE STRICT HYGIENE!  •INHALATION Abdominal pain. Cough. Headache. Drowsiness. Burning sensation. Nausea. Dizziness. Confusion. Blue skin. Blue lips or finger nails. Shortness of breath. Convulsions. Unconsciousness. Symptoms may be delayed (see Notes). Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.  •SKIN Refer for medical attention.  •EYES Redness. Safety goggles or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Gas-tight chemical protection suit including self-contained breathing apparatus. Fireproof if in building. Keep in a well-ventilated room. R: S: UN Hazard Class: 2.3 UN Subsidiary Risks: 5.1 and 8 SEE IMPORTANT INFORMATION ON BACK ICSC: 1311 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards NITRIC OXIDE ICSC: 1311 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS COMPRESSED GAS PHYSICAL DANGERS: CHEMICAL DANGERS: The substance is a strong oxidant and reacts with combustible and reducing materials. On contact with air it emits nitrogen dioxide. OCCUPATIONAL EXPOSURE LIMITS: TLV: 25 ppm as TWA; BEI issued; (ACGIH 2004). OSHA PEL: TWA 25 ppm (30 mg/m3) NIOSH REL: TWA 25 ppm (30 mg/m3) NIOSH IDLH: 100 ppm ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation. INHALATION RISK: A harmful concentration of this gas in the air will be reached very quickly on loss of containment. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes and the respiratory tract . Inhalation of the substance may cause lung oedema (see Notes). The substance may cause effects on the blood , resulting in formation of methaemoglobin. Exposure may result in death. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Lungs may be affected by repeated or prolonged exposure. PHYSICAL PROPERTIES Boiling point: -151.8°C Melting point: -163.6°C Solubility in water, ml/100 ml at 0°C: 7.4 Relative vapour density (air = 1): 1.04 ENVIRONMENTAL DATA N O T E S The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. No odour warning if toxic concentrations are present. Card has been partly updated in April 2005. See sections Occupational Exposure Limits, Emergency Response. Transport Emergency Card: TEC (R)-20S1660 or 20G1TOC NFPA Code: H3; F0; R0; OX ADDITIONAL INFORMATION ICSC: 1311 NITRIC OXIDE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.