International Chemical Safety Cards METHOXYCHLOR ICSC: 1306 1,1-(2,2,2-Trichloroethylidene)bis(4-methoxybenzene) 1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane Dimethoxy-DDT C16H15Cl3O2 Molecular mass: 345.7 ICSC #    1306 CAS #     72-43-5 RTECS # KJ3675000 March 26, 1999 Peer reviewe TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, alcohol-resistant foam, water spray, carbon dioxide. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN!  •INHALATION See Ingestion. Local exhaust or breathing protection. Fresh air, rest.  •SKIN Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Safety spectacles or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Convulsions. Diarrhoea. Nausea. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give plenty of water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment. Personal protection: P2 filter respirator for harmful particles. Separated from food and feedstuffs . Well closed. Keep in a well-ventilated room. Do not transport with food and feedstuffs. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 1306 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards METHOXYCHLOR ICSC: 1306 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS TO LIGHT YELLOW CRYSTALS , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating and on burning producing toxic and corrosive gasesincludinghydrogen chloride (see ICSC 0163). Reacts with oxidants . Attacks some plastics and rubber. OCCUPATIONAL EXPOSURE LIMITS: TLV: 10 mg/m³ as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2004). MAK: (Inhalable fraction) 15 mg/m³; Peak limitation category: II(8); Pregnancy risk group: D; (DFG 2004). OSHA PEL: TWA 15 mg/m3 NIOSH REL: Ca See Appendix A NIOSH IDLH: Potential occupational carcinogen 5000 mg/m3 ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. EFFECTS OF SHORT-TERM EXPOSURE: EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the liver, kidneys, central nervous systeml, when ingested in large amounts. Animal tests show that this substance possibly causes toxic effects upon human reproduction. PHYSICAL PROPERTIES Melting point: 89°C Density: 1.4 g/cm3 Solubility in water: none Vapour pressure: negligible Octanol/water partition coefficient as log Pow: 4.68-5.08 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal. N O T E S Temperature of decomposition unknown in literature. Depending on the degree of exposure, periodic medical examination is suggested. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Maralate, Marlate, Metox, Prentox, Methoxicide are trade names. See also ICSC0034 for DDT. Card has been partly updated in April 2005. See section Occupational Exposure Limits. ADDITIONAL INFORMATION ICSC: 1306 METHOXYCHLOR (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.