International Chemical Safety Cards

METHYLACETOACETATE

ICSC: 1086

Acetoacetic acid methyl ester
Butanoic acid, 3-oxo-, methyl ester
1-Methoxybutane-1,3-dione
C₅H₈O₃
Molecular mass: 116.1
ICSC #    1086
CAS #     105-45-3
RTECS # AK5775000
EC #         607-137-00-0
November 25, 2003 Peer reviewed

TYPES OF HAZARD/ EXPOSURE	ACUTE HAZARDS/ SYMPTOMS	PREVENTION	FIRST AID/ FIRE FIGHTING
FIRE	Combustible.	NO open flames.	Alcohol-resistant foam, powder, carbon dioxide.
EXPLOSION	Above 77°C explosive vapour/air mixtures may be formed.	Above 77°C use a closed system, ventilation.

EXPOSURE
•INHALATION	Cough. Dizziness. Drowsiness. Headache. Sore throat.	Ventilation, local exhaust, or breathing protection.	Fresh air, rest. Refer for medical attention.
•SKIN		Protective gloves.	Remove contaminated clothes. Rinse skin with plenty of water or shower.
•EYES	Redness. Pain.	Safety goggles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION		Do not eat, drink, or smoke during work.	Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water. (Extra personal protection: filter respirator for organic gases and vapours.)

Separated from oxidants.

Xi symbol
R: 36
S: 2-26

SEE IMPORTANT INFORMATION ON BACK

ICSC: 1086

Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

METHYLACETOACETATE

ICSC: 1086

I

M

P

O

R

T

A

N

T

D

A

T

A

PHYSICAL STATE; APPEARANCE:
COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:

CHEMICAL DANGERS:
The substance decomposes on burning producing irritating fumes . Reacts with oxidants .

OCCUPATIONAL EXPOSURE LIMITS:
TLV not established.
MAK not established.

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation of its vapour.

INHALATION RISK:
No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance is irritating to the eyes and the respiratory tract . Exposure may result in lowering of consciousness.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:

PHYSICAL
PROPERTIES

Boiling point: 171.7°C
Melting point: -27°C
Relative density (water = 1): 1.08
Solubility in water, g/100 ml: 50
Vapour pressure, kPa at 20°C: 0.17
Relative vapour density (air = 1): 4.0

Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point:
77°C c.c.
Auto-ignition temperature: 280°C
Explosive limits, vol% in air: 1.4-14.5
Octanol/water partition coefficient as log Pow: -0.26

ENVIRONMENTAL
DATA

N O T E S

NFPA Code: H2; F2; R0;

ADDITIONAL INFORMATION

ICSC: 1086	METHYLACETOACETATE
(C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE:

Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.