International Chemical Safety Cards THIOUREA ICSC: 0680 Thiocarbamide Isothiourea CH4N2S / H2NCSNH2 Molecular mass: 76.1 ICSC #    0680 CAS #     62-56-6 RTECS # YU2800000 UN #        2811 EC #         612-082-00-0 March 13, 2001 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, water spray, foam, carbon dioxide. EXPLOSION Risk of fire and explosion on contact with acrolein. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Cough. Avoid inhalation of fine dust and mist. Local exhaust or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Redness. Face shield or eye protection in combination with breathing protection if powder. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. Wash hands before eating. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Do NOT wash away into sewer. Sweep spilled substance into covered containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment. Chemical protection suit. (Extra personal protection: P2 filter respirator for harmful particles.) Separated from acids, food and feedstuffs , acrolein, oxidants . Cool. Well closed. Keep in a well-ventilated room. Do not transport with food and feedstuffs. Marine pollutant. Xn symbol N symbol R: 22-40-51/53-63 S: 2-36/37-61 UN Hazard Class: 6.1 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0680 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards THIOUREA ICSC: 0680 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: WHITE CRYSTALS OR POWDER . PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing toxic fumes of nitrogen oxides and sulfur oxides . Reacts violently with acrolein, strong acids and strong oxidants . OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK: Class 3b (2000.) ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes . EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the thyroid . This substance is possibly carcinogenic to humans. PHYSICAL PROPERTIES Melting point: 182°C Density: 1.4 g/cm3 Solubility in water: moderate Octanol/water partition coefficient as log Pow: -2.38/-0.95 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. N O T E S Do NOT take working clothes home. Transport Emergency Card: TEC (R)-61G11c ADDITIONAL INFORMATION ICSC: 0680 THIOUREA (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.