International Chemical Safety Cards m-ANISIDINE ICSC: 0375 3-Aminoanisole 3-Methoxyaniline 3-Aminophenol methyl ether 3-Metoxybenzeneamine C7H9NO / H2NC6H4OCH3 Molecular mass: 123.2 ICSC #    0375 CAS #     536-90-3 RTECS # BZ5408000 UN #        2431 October 08, 2002 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Dry powder, water spray, foam, carbon dioxide. EXPLOSION EXPOSURE PREVENT GENERATION OF MISTS! STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Blue lips or finger nails. Blue skin. Confusion. Convulsions. Dizziness. Headache. Nausea. Unconsciousness. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower.  •EYES Face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION (See Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Collect leaking liquid in sealable containers. Do NOT let this chemical enter the environment. Chemical protection suit including self-contained breathing apparatus. Well closed. Separated from food and feedstuffs and strong oxidants . Do not transport with food and feedstuffs. R: S: UN Hazard Class: 6.1 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0375 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards m-ANISIDINE ICSC: 0375 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: PALE YELLOW OILY LIQUID PHYSICAL DANGERS: CHEMICAL DANGERS: On combustion, forms toxic fumes, including nitrogen oxides. Reacts with strong oxidants , causing fire hazard. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance may cause effects on the blood , resulting in the formation of methaemoglobin. Medical observation is indicated. The effects may be delayed. See Notes. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 251°C Melting point: < 0°C Density: 1.1 g/cm3 Solubility in water, g/100 ml at 20°C: 2.05 Vapour pressure, Pa at 25°C: 0.31 Flash point: >112°C Auto-ignition temperature: 515°C Octanol/water partition coefficient as log Pow: 0.93 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. N O T E S Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Health effects of exposure to the substance have not been investigated adequately. See ICSC 0970 o-Anisidine and ICSC 0971 p-Anisidine. Transport Emergency Card: TEC (R)-61S2431 ADDITIONAL INFORMATION ICSC: 0375 m-ANISIDINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.