International Chemical Safety Cards ACETYL BROMIDE ICSC: 0365 Ethanoyl bromide C2H3BrO / CH3COBr Molecular mass: 122.96 ICSC #    0365 CAS #     506-96-7 RTECS # AO5955000 UN #        1716 October 07, 1997 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. NO contact with water. Foam, powder, carbon dioxide, dry sand. NO water. EXPLOSION In case of fire: cool drums, etc., by spraying with water but avoid contact of the substance with water. EXPOSURE AVOID ALL CONTACT!  •INHALATION Abdominal pain. Sore throat. Cough. Burning sensation. Shortness of breath. Laboured breathing. Symptoms may be delayed (see Notes). Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention.  •SKIN Pain. Redness. Blisters. Skin burns. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.  •EYES Pain. Redness. Severe deep burns. Loss of vision. Face shield or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Burning sensation. Abdominal pain. Shock or collapse. Do not eat, drink, or smoke during work. Rinse mouth. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment. Personal protection: complete protective clothing including self-contained breathing apparatus. Separated from food and feedstuffs . See Chemical Dangers. Dry. Well closed. Ventilation along the floor. Do not transport with food and feedstuffs. R: S: UN Hazard Class: 8 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 0365 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards ACETYL BROMIDE ICSC: 0365 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS, FUMING LIQUID , WITH PUNGENT ODOUR. TURNS YELLOW ON EXPOSURE TO AIR. PHYSICAL DANGERS: The vapour is heavier than air. CHEMICAL DANGERS: The substance decomposes on heating producing toxic and corrosive fumesincludinghydrogen bromide and carbonyl bromide. Reacts violently with water, methanol or ethanol to form hydrogen bromide. Attacks many metals in presence of water. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its vapour and by ingestion. INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance and the vapour is corrosive to the eyes, the skin and the respiratory tract. Corrosive on ingestion. Inhalation of its vapour may cause lung oedema (see Notes). The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. PHYSICAL PROPERTIES Boiling point: 76°C Melting point: -96°C Relative density (water = 1): 1.5 Solubility in water: reaction Vapour pressure, kPa at 20°C: 13 Relative vapour density (air = 1): 4.2 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.4 Flash point: 75°C ENVIRONMENTAL DATA The substance is harmful to aquatic organisms. N O T E S Reacts violently with fire extinguishing agents such as water. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered. Transport Emergency Card: TEC (R)-80G14 ADDITIONAL INFORMATION ICSC: 0365 ACETYL BROMIDE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.