International Chemical Safety Cards CHLOROPRENE ICSC: 0133 2-Chloro-1,3-butadiene 2-Chlorobutadiene beta-Chloroprene C4H5Cl / CH2=CClCH=CH2 Molecular mass: 88.5 ICSC #    0133 CAS #     126-99-8 RTECS # EI9625000 UN #        1991 (inhibited) EC #         602-036-00-8 March 27, 1998 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Highly flammable. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames, NO sparks, and NO smoking. Powder, water spray, foam, carbon dioxide. EXPLOSION Vapour/air mixtures are explosive. Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding). Use non-sparking handtools. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE PREVENT GENERATION OF MISTS! STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Cough. Dizziness. Drowsiness. Headache. Sore throat. Unconsciousness. Chest pain. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN MAY BE ABSORBED! Redness. Pain. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Redness. Pain. Corneal damage. Safety goggles, face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Nausea. (See Inhalation). Do not eat, drink, or smoke during work. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. Personal protection: complete protective clothing including self-contained breathing apparatus. Fireproof. Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs , and incompatible materials . See Chemical Dangers. Cool. Keep in the dark. Well closed. Store only if stabilized. Airtight. Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. Marine pollutant. Note: D, E F symbol T symbol R: 45-11-20/22-36/37/38-48/20 S: 53-45 UN Hazard Class: 3 UN Subsidiary Risks: 6.1 UN Packing Group: I SEE IMPORTANT INFORMATION ON BACK ICSC: 0133 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards CHLOROPRENE ICSC: 0133 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID , WITH PUNGENT ODOUR. PHYSICAL DANGERS: The vapour is heavier than air and may travel along the ground; distant ignition possible. As a result of flow, agitation, etc., electrostatic charges can be generated. CHEMICAL DANGERS: The substance can under specific circumstances readily form peroxides, initiating explosive polymerization. The substance may polymerize on standing with fire or explosion hazard. On combustion, forms toxic and corrosive gasesincludingphosgene andhydrogen chloride (see ICSC 0007 and ICSC 0163). Reacts withoxidants, alkali metals and somepowdered metals causing fire and explosion hazard. OCCUPATIONAL EXPOSURE LIMITS: TLV: 10 ppm as TWA; (skin); (ACGIH 2004). MAK: H; Carcinogen category: 2; (DFG 2004). OSHA PEL: TWA 25 ppm (90 mg/m3) skin NIOSH REL: Ca C 1 ppm (3.6 mg/m3) 15-minute See Appendix A NIOSH IDLH: Potential occupational carcinogen 300 ppm ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes , the skin and the respiratory tract . The substance may cause effects on the central nervous system , kidneys and liver . Exposure far above OEL may result in death. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. Chronic exposure may cause alopecia. This substance is possibly carcinogenic to humans. PHYSICAL PROPERTIES Boiling point: 59.4°C Melting point: -130°C Relative density (water = 1): 0.96 Solubility in water, g/100 ml at 20°C: 0.026 Vapour pressure, kPa at 20°C: 23.2 Relative vapour density (air = 1): 3.0 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.57 Flash point: -20°C o.c. Explosive limits, vol% in air: 4-20 Octanol/water partition coefficient as log Pow: 2.1 ENVIRONMENTAL DATA This substance may be hazardous to the environment; special attention should be given to water. It is strongly advised not to let the chemical enter into the environment because it persists in the environment. N O T E S Depending on the degree of exposure, periodic medical examination is suggested. An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert. The odour warning when the exposure limit value is exceeded is insufficient. Do NOT use in the vicinity of a fire or a hot surface, or during welding. Check for peroxides prior to distillation; eliminate if found. Inhibitors such as hydroquinone or phenothiazine are generally added when it is to be stored. Card has been partly updated in October 2004. See sections Occupational Exposure Limits, EU classification, Emergency Response. Transport Emergency Card: TEC (R)-30S1991 NFPA Code: H2; F3; R0 ADDITIONAL INFORMATION ICSC: 0133 CHLOROPRENE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.