Sulfuryl fluoride

IDLH Documentation
CAS number: 2699­79­8

NIOSH REL: 5 ppm (20 mg/m3) TWA, 10 ppm (40 mg/m3) STEL

Current OSHA PEL: 5 ppm (20 mg/m3) TWA

1989 OSHA PEL: 5 ppm (20 mg/m3) TWA, 10 ppm (40 mg/m3) STEL

1993­1994 ACGIH TLV: 5 ppm (21 mg/m3) TWA, 10 ppm (42 mg/m3) STEL

Description of substance: Colorless, odorless gas.

LEL: Nonflammable Gas

Original (SCP) IDLH: 1,000 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the report by Taxay [1966] that less than 5% mortality resulted from exposure of animals for 3 hours to 1,000 ppm.

Short­term exposure guidelines: None developed

ACUTE TOXICITY DATA:

Lethal concentration data:

Species
Reference
LC50

(ppm)
LCLo

(ppm)
Time
Adjusted 0.5-hr

LC (CF)
Derived value
RatNitschke et al. 1986
991
-----
4 hr
1,982 ppm (2.0)
198 ppm
MouseTruhaut et al. 1973
-----
1,200
1 hr
1,500 ppm (1.25)
150 ppm
RabbitTruhaut et al. 1973
-----
5,000
1 hr
6,250 ppm (1.25)
625 ppm

Other animal data: It has been reported that less than 5% mortality resulted from exposure for 3 hours to 1,000 ppm [Taxay 1966].

Human data: None relevant for use in determining the revised IDLH.

Revised IDLH: 200 ppm

Basis for revised IDLH: The revised IDLH for sulfuryl fluoride is 200 ppm based on acute inhalation toxicity data in animals [Nitschke et al. 1986; Truhaut et al. 1973].

REFERENCES:

1. Nitschke KD, Albee RR, Mattsson JL, Miller RR [1986]. Incapacitation and treatment of rats exposed to a lethal dose of sulfuryl fluoride. Fundam Appl Toxicol 7:664­670.

2. Taxay EP [1966]. Vikane inhalation. J Occup Med 8:425­426.

3. Truhaut R, Boudene C, Cluet JL [1973]. Toxicite de quelques derives gazeux fluores et oxyfluores du soufre. Arch Mal Prof 34(10­11):581­591 (in French).

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