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NIOSH REL: The 1989 OSHA PEL may not be protective to workers.
Current OSHA PEL: 25 ppm (100 mg/m3) TWA
1989 OSHA PEL: 10 ppm (40 mg/m3) TWA, 15 ppm (60 mg/m3) STEL
19931994 ACGIH TLV: 5 ppm (12 mg/m3) TWA, 15 ppm (36 mg/m3) STEL
Description of substance: Colorless liquid with a strong, ammonialike odor.
LEL: . . 1.2% (10% LEL, 1,200 ppm)
Original (SCP) IDLH: 1,000 ppm
Basis for original (SCP) IDLH: The chosen IDLH is based on the UCC [1970] report that a 4hour exposure to 1,000 ppm killed 1 of 6 rats.
Shortterm exposure guidelines: None developed
ACUTE TOXICITY DATA:
Lethal concentration data:
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| G. pig
Mouse Rat | Carpenter et al. 1948 Izmerov et al. 1982 Smyth et al. 1951 |
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Other animal data: RD50 (mouse), 184 ppm [Nielsen and Yamagiwa 1989].
Human data: None relevant for use in determining the revised
IDLH.
| Revised IDLH: 200 ppm
Basis for revised IDLH: The revised IDLH for triethylamine is 200 ppm based on acute inhalation toxicity data in animals [Carpenter et al. 1948; Izmerov et al. 1982; Nielsen and Yamagiwa 1989; Smyth et al. 1951]. This may be a conservative value due to the lack of acute inhalation toxicity data for workers. |
REFERENCES:
1. Carpenter CP, Smyth HF Jr, Shaffer CB [1948]. The acute toxicity of ethylene imine to small animals. J Ind Hyg Toxicol 30:26.
2. Izmerov NF, Sanotsky IV, Sidorov KK [1982]. Toxicometric parameters of industrial toxic chemicals under single exposure. Moscow, Russia: Centre of International Projects, GKNT, p. 115.
3. Nielsen GD, Yamagiwa M [1989]. Structureactivity relationships of airway irritating aliphatic amines. Receptor activation mechanisms and predicted industrial exposure limits. Chem Biol Interact 71(23):223244.
4. Smyth HF Jr, Carpenter CP, Weil CS [1951]. Rangefinding toxicity data: list IV. AMA Arch Ind Hyg Occup Med 4:119122.
5. UCC [1970]. Toxicology studies: triethylamine. New York, NY: Union Carbide Corporation.
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